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ARTEMETHER-LUMEFANTRINE; UNDERSTANDING THE CLOCK

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Written by Timothy Okooboh                           The Artemether-lumefantrine clock Recently, there have been widespread reports regarding the ineffectiveness of Artemether-lumefantrine for the treatment of malaria infection. This treatment failure is mostly due to a poor understanding of the correct dosage interval of Artemether-lumefantrine, that is, the various times of the day the drug should be taken during the three day therapy. Below are two common case scenarios of a health care provider and patient interaction that take place in health care facilities across the world especially Sub-Saharan Africa where malaria is most prevalent. Scenario one Health care provider : Good morning madam. This is Artemether-lumefantrine 80/480 mg. It is a medicine that will take care of your malaria infection. Take one tablet when you get home and one tablet 8 hrs later. Then from tomorrow, take one tablet ...
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DIABETIC FOOT CARE

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Written by Timothy Okooboh Diabetes mellitus is one of the leading causes of non-traumatic lower extremity amputation (LEA) worldwide. Prevalence rates of diabetic foot lesions vary from 0.9 - 8.3 % in Nigeria. Diabetes is a disease in which blood glucose levels are elevated either as a result of insulin deficiency or impaired sensitivity of insulin receptors. Insulin is the hormone that promotes the absorption of glucose into the liver, fat and skeletal mucles. Therefore, problems with insulin secretion or impaired response to insulin production will lead to the build up of glucose in the blood, known as hyperglycemia. Complications due to diabetes can be classified into two groups: macrovascular and microvascular complications. Macrovascular complications due to diabetes include coronary artery disease, peripheral arterial disease and stroke. Microvascular complications due to diabetes include diabetic neuropathy, diabetic retinopathy and diabetic nephropathy. Peripheral ...
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Skin Health; Understanding Skin Lesions

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Written by Timothy Okooboh It was 7.00 Am on Monday morning. Aliyu's mom walked into her five year old son's room to prepare him for school. But to her surprise, she noticed an unusual appearance on his face, around his nose and mouth. Oh my God! What are these? She said. She placed the palm of her hands around his neck to feel his temperature and observed that it was slightly higher than normal. She hurriedly took him to a nearby health centre, panting and beckoned to a nurse to take her to the doctor. Calm down madam said the nurse, what is the matter? It's my son, said the mother, he is not alright. I need to see the doctor immediately. Finally, it got to their turn. After one minute of physical examination, the doctor said, your son has some reddish crusts and blisters around his nose and mouth. This is impetigo. Impeti what? Said Aliyu's mom. Oh don't panic madam. Impetigo is a bacteria skin infection. I will prescribe an antibiotic for Aliyu. He will ...
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